Stromal cell. The International Society for Cellular Therapy position …

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Stromal cell. The International Society for Cellular Therapy position statement. Cytotherapy 2006, 8:315?17. 44. Zhang Y, Huang P, Jiang T, Zhao J, 3-Bromo-5-chloro-2-fluoroaniline Zhang N: Role of aldose reductase in TGF-beta1-induced fibronectin synthesis in human mesangial cells. Mol Biol Rep 2010, 37:2735?742. 45. Colotta F, Sciacca FL, Sironi M, Luini W, Rabiet MJ, Mantovani A: Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin. Am J Pathol 1994, 144:975?85.Chen et al. Stem Cell Research Therapy 2014, 5:36 http://stemcellres.com/content/5/2/Page PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/13485127 11 of46. Duhamel-Clerin E, Orvain C, Lanza F, Cazenave JP, Klein-Soyer C: Thrombin receptor-mediated increase of two matrix metalloproteinases, MMP-1 and MMP-3, in human endothelial cells. Arterioscler Thromb Vasc Biol 1931?938, 1997:17. 47. Shankar R, PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21715270 de la Motte CA, Poptic EJ, DiCorleto PE: Thrombin receptoractivating peptides differentially stimulate platelet-derived growth factor production, monocytic cell adhesion, and E-selectin expression in human umbilical vein endothelial cells. J Biol Chem 1994, 269:13936?3941. 48. Macfarlane SR, Seatter MJ, Kanke T, Hunter GD, Plevin R: Proteinaseactivated receptors. Pharmacol Rev 2001, 53:245?82. 49. Coughlin SR: How the protease thrombin talks to cells. Proc Natl Acad Sci U S A 1999, 96:11023?1027. 50. Lidington EA, Steinberg R, Kinderlerer AR, Landis RC, Ohba M, Samarel A, Haskard DO, Mason JC: A role for proteinase-activated receptor 2 and PKC-epsilon in thrombin-mediated induction of decay-accelerating factor on human endothelial cells. Am J Physiol Cell Physiol 2005, 289:C1437 1447. 51. Stanisavljevic J, Porta-de-la-Riva M, Batlle R, de Herreros AG, Baulida J: The p65 subunit of NF-kappaB and PARP1 assist Snail1 in activating fibronectin transcription. J Cell Sci 2011, 124:4161?171. 52. Dooley A, Shi-Wen X, Aden N, Tranah T, Desai N, Denton CP, Abraham DJ, Bruckdorfer R: Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate. Rheumatology (Oxford) 2010, 49:2024?036. 53. Lin CL, Wang FS, Kuo YR, Huang YT, Huang HC, Sun YC, Kuo YH: Ras modulation of superoxide activates ERK-dependent fibronectin expression in diabetes-induced renal injuries. Kidney Int 2006, 69:1593?600. 54. Ender M, Andreoni F, Zinkernagel AS, Schuepbach RA: Streptococcal SpeB cleaved PAR-1 suppresses ERK phosphorylation and blunts thrombininduced platelet aggregation. PLoS One 2013, 8:e81298. 55. Lin H, Trejo J: Transactivation of the PAR1-PAR2 heterodimer by thrombin elicits beta-arrestin-mediated endosomal signaling. J Biol Chem 2013, 288:11203?1215. 56. Lin CH, Yu MC, Chiang CC, Bien MY, Chien MH, Chen BC: Thrombininduced NF-kappaB activation and IL-8/CXCL8 release is mediated by c-Src-dependent Shc, Raf-1, and ERK pathways in lung epithelial cells. Cell Signal 2013, 25:1166?175. 57. Delekta PC, Apel IJ, Gu S, Siu K, Hattori Y, McAllister-Lucas LM, Lucas PC: Thrombin-dependent NF-kappaB activation and monocyte/endothelial adhesion are mediated by the CARMA3.Bcl10.MALT1 signalosome. J Biol Chem 2010, 285:41432?1442.doi:10.1186/scrt424 Cite this article as: Chen et al.: Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells ijms17122034 via the protease-activated receptor mediated signalling pathways. Stem Cell Research Ethyl 5-bromo-6-chloropicolinate Therapy 2014 5:36.Submit your next manuscript to BioMed Central and take full advantage of:?Convenient online submission ?T.

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